21 Years After FDA Approval, Abortion Pill Is More Critical Than Ever

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21 Years After FDA Approval, Abortion Pill Is More Critical Than Ever
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Abortion pills are safe and effective, widely accessible online and easy to use.

The abortion pill mifepristone used in combination with another medication—misoprostol—can safely and effectively end a pregnancy. Mifepristone interrupts the flow of the hormone progesterone that sustains a pregnancy and misoprostol causes contractions to expel the contents of the uterus. mifepristone, known as RU-486, in 1980. Chemist Georges Teutsch first synthesized mifepristone and endocrinologist Étienne-Émile Baulieu arranged tests of its use for medical abortion.

The same year, anti-abortion protests in France caused Rousel-Uclaf’s owner Hoechst AG of Germany to stop distributing mifepristone. The French government responded by ordering Roussel-Uclaf to resume selling the medication in the interest of public health. at the time, “I could not permit the abortion debate to deprive women of a product that represents medical progress.

including the U.S. National Right to Life Committee, Roussel-Uclaf and Hoechst AG declined to bring the drug to the U.S. market for fear of boycotts and lost profits. Instead, the company donated all rights for medical uses of mifepristone in the U.S. to the Population Council—a nonprofit that conducts international research on reproductive health.

The Population Council then tried to find a large drug company willing to develop the drug for the U.S. market. After threatened boycotts from anti-abortion groups, large drug companies refused, so in 1995, the Population Council

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