A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy - Nature Medicine

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A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy - Nature Medicine
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Conserved microbiome features across clinical and geographical variations may enable microbiome-based predictions of outcomes in CD19-CAR-T cell immunotherapy EranElinav MichaelDJain

We thank the members of the DKFZ Microbiome & Cancer Division and the Elinav laboratory, Weizmann Institute of Science for insightful discussions; and the participants, investigators, collaborators and study site personnel engaging in the trials. We also thank the REG allo-SCT/CAR team, especially H. Bremm, T. Schifferstein and Y. Schumann for their help in collecting and cryopreserving stool samples, and S. Gleich for data management.

Christoph K. Stein-Thoeringer, Eli Zamir, Sabine Schmidt, Roman Rohrbach, Rogier Gaiser & Eran Elinav Neeraj Y. Saini, Paolo Strati, Ranjit Nair, Dai Chihara, Luis E. Fayad, Sairah Ahmed, Swaminathan P. Iyer, Raphael E. Steiner, Preetesh Jain, Loretta J. Nastoupil, Jason Westin, Reetakshi Arora, Michael L. Wang, Christopher R. Flowers & Sattva S.

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