A promising vaginal lube contraceptive works by engineering mucus instead of killing sperm

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A promising vaginal lube contraceptive works by engineering mucus instead of killing sperm
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  • 📰 IntEngineering
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“Vaginal gels like this can be applied in seconds.”

that the results demonstrate the potential of an unprecedented approach to preventing unwanted pregnancies. I.e., one that blocks sperm by engineering mucus rather than killing sperm cells as spermicides do.Better yet, the chitosan gel didn't inflame the vaginal walls like chemical spermicides, another non-hormonal birth control method, do. This could mean the gel will be less of an annoyance.

“Vaginal gels like this can be applied in seconds,” Crouzier says. “We imagine that a product like this should be usable from seconds to a few hours before sexual intercourse. The effect could last for hours, but diminish over time as the mucus barrier is replaced naturally.”Significantly, laboratory tests utilizing human cervical mucus and sperm revealed that the chitosan gel had a similar impact.

According to studies cited by Crouzier, about 50 percent of women believe their contraceptives must be hormone-free. Thankfully, this study provides a clear step forwards in 'topically' achieving that. Crouzier founded a company called Cirque Biomedical and has since entered a $360 million partnership with the women’s health company, Organon, with the aim to develop and commercialize the new gel.Close to half of the world's pregnancies are still unplanned, reflecting a clear unmet need in contraception. Ideally, a contraceptive would provide the high efficacy of hormonal treatments, without systemic side effects.

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