The new, wearable device monitors tumor size. A compact, autonomous device with a stretchable and flexible sensor has been developed by Stanford University engineers to assess the changing size of tumors under the skin. The battery-powered, non-invasive device can wirelessly transmit findings to a
The new, wearable device monitors tumor size.Stanford University
The researchers claim that their FAST device, which stands for “Flexible Autonomous Sensor measuring Tumors,” is a completely novel, fast, affordable, hands-free, and accurate method of evaluating the effectiveness of cancer drugs. On a larger scale, it might pave the way for exciting new directions in cancer treatment. The researchers’ findings were recently published in the journalResearchers use mice with subcutaneous tumors to test thousands of potential cancer drugs every year.
The use of metal pincer-like calipers to measure soft tissues is not ideal, and radiological approaches cannot deliver the sort of continuous data needed for real-time assessment. FAST can detect changes in tumor volume on the minute-timescale, while caliper and bioluminescence measurements often require weeks-long observation periods to read out changes in tumor size.FAST’s sensor is composed of a flexible and stretchable skin-like polymer that includes an embedded layer of gold circuitry.
The breakthrough is in FAST’s flexible electronic material. Coated on top of the skinlike polymer is a layer of gold, which, when stretched, develops small cracks that change the electrical conductivity of the material. Stretch the material and the number of cracks increases, causing the electronic resistance in the sensor to increase as well. When the material contracts, the cracks come back into contact and conductivity improves.
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