A topical ED drug made from deadly spider venom just cleared its first human trial

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A topical ED drug made from deadly spider venom just cleared its first human trial
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A new ED drug created from deadly spider venom will enter the second phase of its human trials this month.

The Brazilian wandering spider is also known as the banana spider and is actually rather large. Being bit by this spider can cause elevated heart rate, shock, convulsions, and even death. A side effect of the bite is that it can also cause erections that last for hours on end. This is known as priapism, and while it can cause permanent damage to the penis and is painful, the fact this spider bite causes it has long interested many scientists.

The topical gel the researchers created appears to work with minimal amount applied to the penis. The trial has shown that it can increase blood flow by increasing the level of nitric oxide – a molecule that is vital to erections – without reaching a level of toxicity in the bloodstream. Topical treatments like this often have fewer, which is why we’re seeing so much interest in using the spider’s venom to create a gel-like treatment option.

From here the spider venom ED drug will go on to additional testing, where it will see a much larger scale of testing. That phase is set to begin within the month and will focus on testing it on patients who have undergone prostate removal, which can damage the nerves that help maintain an erection. The study will include 72 people, all of whom will be broken up into three groups to test the drug’s efficacy against other options.

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