Are claims that Berberine is ‘nature’s Ozempic’ overblown?

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Are claims that Berberine is ‘nature’s Ozempic’ overblown?
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Berberine is a plant extract that has many benefits, including blood sugar control and cholesterol reduction. Here's what experts say about recent claims it can help with weight loss too.

, which reduces hunger. In contrast, berberine’s mechanism of action for weight loss most likely derives from its effects on blood sugar levels.

If the goal is weight loss, says Dan Azagury, a physician at Stanford University who specializes in treating obesity, the safest, most effective way to accomplish that is to seek out the help of a doctor who specializes in treating obesity. “If you have a heart problem, you go to your cardiologist. If you have obesity, you go to a weight loss clinic that is established and reputable.”

“We’re entering an age where the time for being desperate and trying unsafe things to lose weight is over," says Azagury."The treatments are here.”The major advantage of medications such as Ozempic, Wegovy, or Mounjaro, is that they are required to clear a, which requires a substantial body of research showing a drug is safe and effective. Even after these medications are on the market, they are still monitored, which includes assessing the impact of long-term use.

For a supplement like berberine, although there have been multiple studies on its effectiveness, these studies have been far more limited in scope, and there is no data on whether it is safe to consume for long periods.One of the most significant differences between a medication like Ozempic and a supplement like berberine is the method by which it is regulated by the FDA. For medications,

, which includes additional oversight methods for ensuring that patients are receiving a product that is safe, and that contains the stated ingredients and dosage., where the regulatory mechanisms to ensure quality and safety are completely different. The FDA is “not going to control what you eat with the same system as you control with the drugs you take,” Azagury says.

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