A blood test has been developed that could diagnose Alzheimer’s years before symptoms develop.
The toxic bundles, or ‘oligomers’, form over decades –Currently the disease is diagnosed once devastating memory loss and confusion has already taken hold. By that point, it’s too late for drugs that target the cause.
‘That’s important for individuals’ health and for all the research into how toxic oligomers of amyloid beta go on and cause the damage that they do.In a trial of more than 300 people SOBA detected amyloid beta clumps in the blood of ten who showed no signs of cognitive impairment when it was collected.
They could also offer hope of national screening programs – with older people being checked during routine visits to the GP. Their technique then uses standard methods to confirm the clumps attached to the test surface are made up of amyloid beta. They also showed it could easily be modified to detect toxic oligomers of another type of protein associated with Parkinson’s disease and Lewy body dementia.
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