Breakingviews - Eli Lilly gorges on obesity options

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Breakingviews - Eli Lilly gorges on obesity options
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Eli Lilly has filled its plate with potential obesity treatments, unveiling data from two more on Monday. One offers the convenience of a pill; the other, with the scientific name retatrutide, led to patients losing an astonishing 24% of their weight at the highest dose.

, but is this just more pharmaceutical R&D overkill? Perhaps, but there are justifiable reasons for it.

While doctors are reluctant to switch patients from working therapies, theoretically giving an advantage to first movers, drugs vary in effectiveness, side effects and convenience. Pfizer’s cholesterol-lowering Lipitor, for one, reached consumers after rivals, and a decade after Merck’s version. Yet its higher ability in reducing cholesterol, along with aggressive marketing, made Lipitor the best-selling drug worldwide for years, with total revenue topping $150 billion.

Lilly’s research budget, projected at 24% of revenue this year, exceeds that of many peers, including Pfizer’s

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Eli Lilly Experimental Obesity Drug Could Beat Rivals in Total Weight Loss for PatientsObese or overweight patients who took Eli Lilly’s retatrutide lost 58 pounds on average, the pharmaceutical company said in a mid-stage clinical trial.
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Daily pill from Eli Lilly leads to 15% weight loss in midstage study, rivaling Wegovy results without the shotEli Lilly’s experimental pill for weight loss helped people lose an average of 15% of their body weight after 36 weeks on the highest dose in a midstage trial.
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