Vaccinated patients with cancer are more likely than those without cancer to contract a breakthrough COVID-19 infection, which puts them at a much higher risk for hospitalization and death, according to new study.
The risks were highest among patients who had certain cancers and those who had received cancer treatment within the past year.
Researchers at Case Western Reserve University analyzed electronic health record data for more than 636,000 vaccinated patients, including more than 45,000 vaccinated patients with cancer. They looked for the time trends, risks and outcomes of breakthrough COVID-19 infections for vaccinated cancer patients in the U.S. between December 2020 and November 2021.
Patients who had medical encounters for their cancer within the past year had a higher risk for a breakthrough infection, particularly those with breast cancer, blood cancers, colorectal cancer, bladder cancer and pancreatic cancer. Among patients who didn’t have cancer, the overall hospitalization risk was 25.9% in patients with a breakthrough infection, as compared with 3% in those without a breakthrough infection. The overall risk of death was 2.7% after a breakthrough infection, as compared with .5% in those without a breakthrough infection.
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