Cancer drug shortages are creating dire circumstances for some patients

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Cancer drug shortages are creating dire circumstances for some patients
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A shortage of cancer medications has created dire circumstances for many patients diagnosed with the disease, forcing them — along with their doctors — to make difficult decisions.

After several unsuccessful rounds of chemotherapy, his doctor, Alan Tan of Rush University Medical Center in Chicago, recommended that he switch to Pluvicto, a new medication for advanced prostate cancer.. Landfair is now on a waitlist for the medication, which isn’t expected to be widely available for several more months.His family says his cancer is “aggressive and still growing.”

According to the Food and Drug Administration, there are four cancer drugs in shortage: Pluvicto, for advanced prostate cancer, as well as methotrexate, cisplatin and fluorouracil, commondrugs used to treat a broad range of cancers from the skin to the bones and lungs. A fifth drug, a bladder cancer therapy called BCG, is also said to be in shortage, according to Dr. Vignesh Packiam, a urologist at the University of Iowa Hospitals and Clinics.

“There’s little incentive to invest in generic manufacturing, oftentimes, especially for these much older drugs — the margins aren’t very big,” Ganio said. “It’s almost a disincentive.”

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