.drwilner and Selim Benbadis, MD, discuss cannabidiol for absence epilepsy.
We did it because, as you know, for typical absence seizures, there are very few options to treat. The only two medications over decades that we know work for typical absence seizures are valproate and ethosuximide. If those do not work, the options are completely off-label.
Our question was whether it's a newer drug, it's approved, and it works for some types of seizures; might it work for typical absence seizures?Benbadis: We did it in what I think is an elegant and objective way, which is by EEG. We performed a 24-hour home EEG. Patients had to have a certain number of spike-wave complexes because we needed something to measure. We measured objectively the spike-wave burden. How many seconds in 24 hours does this patient spend in spike-wave complexes?
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