Characterization of anti-orthopoxvirus antibody response in general population and gay men medrxivpreprint OrthopoxVirus Mpox MpoxVIrus AntibodyResponse
By Dr. Sanchari Sinha Dutta, Ph.D.Dec 22 2022Reviewed by Aimee Molineux A team of China-based scientists has recently estimated and compared the levels of anti-mpox and anti-vaccinia antibodies in gay men and the general population. The study is currently available on the medRxiv* preprint server.
Smallpox is a life-threatening infection caused by the variola virus, which also belongs to the same Orthopoxvirus genus. Vaccines developed against smallpox are, thus, expected to provide cross-protection against mpox infection. In the current study, scientists have estimated and compared the blood levels of anti-mpox and anti-vaccinia antibodies in MSM and the general population residing in China. They have also compared the antibody responses in people born before and after 1981. In China, the smallpox vaccination ended in 1981.
Peripheral blood samples were collected from the participants to measure the levels of binding and neutralizing antibodies targeting specific proteins of the mpox virus and vaccinia virus. Neutralizing antibody response The scientists measured the levels of anti-vaccinia neutralizing antibodies with the speculation that the antibodies may provide a cross-reactive neutralizing response against the mpox virus.
The analysis identified a positive correlation between anti-mpox and anti-vaccinia binding antibody responses in general adults born before 1981. However, no such correlation was detected in MSM and general adults born after 1981.
Australia Latest News, Australia Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Christmas beetles: Scientists ask Australians for help finding missing festive bugsSeen as a symbol of Christmas in Australia, the beetles seem to have gone missing in recent years.
Read more »
Scientists uncover ‘first record of a dinosaur eating a mammal’Palaeontologists in the UK have analysed fossil remains from around 120 million years ago, showing a small, feathered dinosaur – known as Microraptor – with the foot of an animal inside its ribcage.
Read more »
“Living Solar Cell” Could Pave The Way For Future Sustainable Energy Tech | OilPrice.comThe researchers say that their method could enable the development of future sustainable, multifunctional green energy technologies.
Read more »
Scientists uncover first record of a dinosaur eating a mammal in fossil from 120 million years agoPalaeontologists in the UK analysed fossil remains of a small, feathered dinosaur, known as a microraptor, and found it appeared to have eaten a small mammal about the size of a mouse.
Read more »