Scientists say simultaneous infection with viruses may explain rise in cases, with 12 UK children requiring liver transplants
Simultaneous infection with two common viruses is thought to explain a recent surge inTwo research groups have detected high levels of adeno-associated virus 2 – a little-known virus not previously associated with human disease – in almost all of the affected British children they have tested. AAV2 is unable to replicate by itself but can do so in the presence of a second virus.
“My feeling is that this has probably happened before. But because there have been some changes in the seasonal trends of these viruses, we’ve seen a small collection of cases all at once, and that’s why we’ve picked them up,” said Prof Emma Thomson, a consultant in infectious diseases at the MRC-University of Glasgow Centre for Virus Research, who was involved in the new research.
was to blame, because they were commonly found in samples from affected children. Another idea was that Covid infections had left children more susceptible to hepatitis. Both studies were able to rule out recent or prior Covid infection as a direct cause for the acute hepatitis – although neither has been peer reviewed.
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