Emily is a health news writer based in London, United Kingdom. She holds a bachelor's degree in biology from Durham University and a master's degree in clinical and therapeutic neuroscience from Oxford University. She has worked in science communication, medical writing and as a local news reporter while undertaking journalism training. In 2018, she was named one of MHP Communications' 30 journalists to watch under 30. ([email protected])
Most microbes perish when exposed to common cleaning products, but the residue from those disinfectants may be driving deadly bacteria to become resistant to antibiotics, a lab study suggests.
"Our finding suggests that biocides at low concentration can compromise antibiotic potency and lead to the development of antibiotic resistance," Liping Li, lead study author and research fellow at Macquarie University in Sydney, told Live Science in an email."We propose that further investigation and survey about the side effects of residual biocides in real world scenarios are necessary to warrant that we are using these precious chemicals wisely and safely," he added.
The authors of the new study introduced mutations into the genome of A. baumannii to determine which genes would help the bacteria survive when treated with 10 biocides. By exposing the mutant bacteria to different cleaners, they identified several of these survival genes; some coded for proteins in the wall that surrounds bacterial cells, and others coded for proteins inside the cells, including proteins involved in metabolism or respiration, the process by which cells make fuel.
Antibiotics that target the cell envelope were not affected and could still kill the microbe. The authors hypothesized that this is because the inside-targeting antibiotics were less likely to be imported, likely because this process requires energy from the cell, which would make them less potent against A. baumannii.
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