Symptom profiles between individuals with prior COVID-19 and those with other acute respiratory infections (ARIs).
By Tarun Sai LomteOct 10 2023Reviewed by Lily Ramsey, LLM In a recent study published in eClinicalMedicine, researchers compared symptom profiles between individuals with prior coronavirus disease 2019 and those with other acute respiratory infections .
Post-acute infection syndromes often remain undiagnosed due to diverse symptoms and the lack of diagnosis tests. Further, research on post-acute sequelae of SARS-CoV-1, influenza, and Middle-East respiratory syndrome has been limited to those with severe illness. In contrast, long COVID has been studied in individuals with all severity levels.
SARS-CoV-2 infection was defined as a positive SARS-CoV-2 swab or antibody test. Non-COVID-19 ARI was described as a self-report or hospital diagnosis of common cold, influenza, pneumonia, pharyngitis, tonsillitis, bronchitis, ear infection, or other lower/upper respiratory infections. The prevalence and severity of 16 COVID-19 symptoms were assessed.
The prevalence and severity of symptoms among COVID-19 subjects were higher than those without infection, irrespective of whether the infection occurred more than 12 weeks before. The moderate class showed a slightly higher probability of having all 16 symptoms but had a larger increase in sleep problems, PHQ-4 score, joint/muscle pain, and difficulty concentrating. The severe class showed a marked increase in symptom prevalence and severity, with the largest increases in dizziness, memory problems, and difficulty concentrating.
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