A study conducted in Iran and published in BMCPregnancyChildbirth finds lower levels of copper and zinc in mothers with preterm delivery, showing their biological role in the pathogenesis of preterm delivery. However, more extensive studies are required.
]. Several studies indicated that deficiency in copper and zinc during pregnancy is associated with low birth weight and preterm delivery; however, this is not confirmed by all the existing studies. This study can help identify the pathogenesis of preterm delivery in countries marked by micronutrient deficiencies, particularly in Asian countries [].
The gestational age was estimated based on the first day of the last menstrual period or the first-trimester ultrasound, and the ultrasound criterion was accepted with a difference of more than ten days. Mothers in both groups were matched for pregnancy and childbirth rating, BMI at pregnancy, education level, income, and employment status.A researcher was present in the obstetrics and gynecology ward of Allameh Bohloul Hospital, Iran for the whole sampling process which took 11 months.
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