More than 300 children in Gambia, Indonesia and Uzbekistan died of acute kidney injury linked to contaminated cough syrup, prompting the WHO to call for action to prevent further deaths. Most of those who died were under the age of five.
, requesting some"substandard products" are removed from circulation to"prevent harm to patients".
The alerts covered some cough syrups made by India's Maiden Pharmaceuticals and Marion Biotech, as well as similar medicines made by four Indonesian manufacturers - PT Yarindo Farmatama, PT Universal Pharmaceutical, PT Konimex and PT AFI Pharma - that were sold domestically.The companies involved have either denied that their products have been contaminated or declined to comment while investigations are ongoing.
It also asked governments and regulators to assign resources to inspect manufacturers, increase market surveillance and take action where required. While manufacturers should only buy raw ingredients from qualified suppliers, test their products more thoroughly and keep records of the process, the WHO added.
The WHO also said suppliers and distributors should check for signs of falsification and only distribute or sell medicines authorised for use.
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