Dearth of high quality monkeypox guidelines may be hampering care globally GlobalHealthBMJ
A dearth of high quality, up to date clinical guidance on monkeypox may be hampering effective and safe treatment of the infection around the world, concludes a review of what's available to guide patient care and published in the open access journalExisting guidance, such as it is, too often lacks sufficient detail, fails to include different groups, and is contradictory, say the researchers.
They therefore set out to assess the availability, quality, scope and inclusivity of available international clinical guidance on the treatment and supportive care of patients with monkeypox infection. There was little provision for different risk groups: only 5 provided any advice for children; and only 3 provided advice for pregnant women or for people living with HIV.
While cidofovir and brincidofovir are active against pox viruses in laboratory studies, there are few data on how well they treat pox viruses in people, added to which they are only authorized for use in certain countries, note the researchers.
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