Deconstructing dissociation: a triple network model of trauma-related dissociation and its subtypes - Neuropsychopharmacology

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Deconstructing dissociation: a triple network model of trauma-related dissociation and its subtypes - Neuropsychopharmacology
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Investigators shed new light on brainactivity related to dissociative symptoms

Trauma-related pathological dissociation is characterized by disruptions in one’s sense of self, perceptual, and affective experience. Dissociation and its trauma-related antecedents disproportionately impact women. However, despite the gender-related prevalence and high individual and societal costs, dissociation remains widely underappreciated in clinical practice. Moreover, dissociation lacks a synthesized neurobiological model across its subtypes.

Participants were 91 women with and without: a history of childhood trauma, current posttraumatic stress disorder , and varied levels of dissociation. Participants provided clinical data about dissociation, PTSD symptoms, childhood maltreatment history, and completed a resting-state functional magnetic resonance imaging scan. We used a novel statistical approach to assess both overlapping and unique contributions of dissociation subtypes.

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