A trial spanning more than 20 years and almost 1,000 participants worldwide has found an important result – people with a condition that gives them a higher chance of developing certain cancers can reduce the risk of some of those cancers by more
Those who've inherited Lynch syndrome genes have a significantly increased risk of developing colorectal cancer, as well as gastric, endometrial, ovarian, pancreatic, prostate, urinary tract, kidney, bile duct, small bowel, and brain cancers.
Another 455 people with Lynch syndrome took a daily placebo that looked like powdered starch but didn't contain active ingredients. The original trial was called the CAPP2 study, and the team are now carrying out a follow-up called CaPP3, involving more than 1,800 people with Lynch syndrome.
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