Disrupted rhythms of rest and wakefulness contribute to worse symptoms in schizophrenia patients, finds study

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Disrupted rhythms of rest and wakefulness contribute to worse symptoms in schizophrenia patients, finds study
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In a paper published today in Molecular Psychiatry, a team of scientists from the University of Pittsburgh in collaboration with researchers in Italy described shared patterns of sleep disturbances and irregularities in daily rhythms of rest and activity across patients with schizophrenia spectrum disorder, or SSD.

that were predictive of worse SSD symptoms and correlated with poorer quality of life.

In addition, sedative medications that are used to manage SSD symptoms are known to alter sleep and extend the time that patients spend resting up to 15 hours per day. Too much sleep can have"It's important to be mindful of how drugs that we prescribe to patients affect their health more broadly," he said."Our study shows that a 12- to 15-hour sleep can be harmful, and it's important to avoid overprescribing sedatives and use the lowest dose possible.

They found that both residential and outpatient SSD individuals tended to have fewer active hours during the day and spent more time sleeping or passively resting than healthy controls.

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