Prime editing: DNA tool could correct 89% of genetic defects
How can prime editing treat disease?
A mutation that turned one specific A into a T results in the most common form of sickle cell disease.Tay-Sachs disease, a rare and fatal nerve condition, is often caused by the addition of four extra letters of code. The other 11% include times when people have too many copies of a gene or when the whole gene is missing.
That would apply to some blood disorders like sickle cell or thalassemias, where bone marrow can be removed and put back in.
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