Research at the Francis Crick Institute could lead to new drugs to counter progress of diseases like Alzheimer’s
British scientists are about to launch a remarkable research project that will demonstrate how the air we breathe can affect our brains. This work will be vital, they say, in understanding a major medical problem: how atmospheric pollution can triggeris one of the most pernicious threats to human health and have shown it is involved in causing cancer, heart disease, diabetes, low birthrates, and many health conditions.
A key type of air pollution consists of suspensions of minuscule fragments of solids and liquid droplets. These are produced from car and truck exhausts, factories, dust, pollen, volcanoes, wildfires and other sources and are known as particulate matter 2.5 or simply PM2.5. Exactly how this process unfolds and leads to dementia is not clear, however, and a major aim of the Rapid project will be to reveal the precise process that causes PM2.5s to cause brain tissue to form the clumps that are the hallmark of Alzheimer’s disease.
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