The data bolsters Eli Lilly's position in the budding weight loss drug market and establishes the company as a formidable competitor to Novo Nordisk.
Another trial, called Surmount-3, evaluated tirzepatide in more than 500 patients who first engaged in "intensive lifestyle interventions" for 12 weeks. That included a low-calorie diet, exercise and weekly counseling sessions.
Those who took tirzepatide lost an additional 21.1% of their weight on average, while patients in the placebo group gained back 3.3% of their weight on average. The findings from the trial "challenge the notion that patients living with obesity or overweight can achieve their weight loss goals with diet and exercise alone," according to Emmick.
The results follow groundbreaking data released last month on a different Eli Lilly drug called retatrutide. The experimental obesity drug helped patients loseLike Ozempic and Wegovy, Eli Lilly's tirzepatide is a weekly injection that changes the way patients eat and leads to decreased appetite by mimicking certain hormones in the gut.
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