Exercise training can lead to a significant reduction in liver fat for patients with nonalcoholic fatty liver disease, a leading cause of liver disease worldwide, a new study finds.
People in the study needed about 150 minutes per week of moderate-intensity exercise, such as brisk walking, or 75 minutes per week of vigorous-intensity exercise, such as jogging or cycling.
NAFLD affects nearly 30% of people worldwide. Over time, it can lead to cirrhosis and cancer. Exercise training has shown multiple benefits for patients with NAFLD, including improvements in liver fat, physical fitness, body composition, vascular biology, and health-related quality of life. Among 14 studies with 551 participants, the average age was 53, and the average body mass index was 31. The studies ranged from 4 to 52 weeks and included different types of exercise training, such as aerobic, high-intensity interval training, resistance training, and aerobic plus resistance training. The average weight loss was about 2.8% among those who participated in exercise training.
For all 14 studies, an exercise dose of 750 or more metabolic equivalent of task minutes per week resulted in a significant response. This equals 150 minutes per week of moderate-intensity exercise, such as brisk walking, or 75 minutes per week of vigorous-intensity exercise, such as jogging or cycling.
At this time, there is no consensus from leading professional societies regarding the optimal physical activity program for patients with NAFLD, the study authors write. That said, most current clinical guidelines support at least 150 minutes per week of moderate-intensity aerobic activity.
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