Two types of adipocytes (fat cells) were infected in the laboratory: one obtained from human stem cells isolated from subcutaneous tissue and the other differentiated from stem cells taken from visceral fatty tissue. Experiments show that visceral fat – fat around the liver, intestines, and other o
Cultured differentiated adipocytes: lipids are stained red; the protein ACE-2, which serves as the receptor for SARS-CoV-2, is green; cell nuclei are blue. Credit: Amanda Passos & Flávio Protasio Veras
In order to arrive at this conclusion, Marcelo Mori, a professor at the Institute of Biology at UNICAMP and one of the study’s leaders, infected in the lab two different types of fat cells: one obtained from human stem cells isolated from subcutaneous tissue and the other differentiated from stem cells taken from visceral fatty tissue.SARS-CoV-2
The group then decided to investigate whether there were differences between the way visceral and subcutaneous adipose cells responded to infection. As far as metabolic diseases are concerned, the evidence in the scientific literature shows visceral fat to be the main villain, while subcutaneous fat tends to be neutral or even beneficial.
“Our hypothesis is that this represents an antiviral cellular response,” Mori said. “There are studies showing that inhibition of lipolysis lowers the replicative capacity of SARS-CoV-2, which can be explained by the fact that the virus needs lipids to produce its envelope, as well as energy from cells to make copies of its genetic material.” Reduced lipolysis in subcutaneous adipose tissue, therefore, could be positive for the patient and bad news for the virus.
Australia Latest News, Australia Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Billy Joel Postpones Last Madison Square Garden Show of the Year After Contracting ‘Viral Infection’Billy Joel has postponed his final Madison Square Garden concert of the year, initially slated for Monday evening, due to a “viral infection.” On Saturday evening, reps for the singer s…
Read more »
Billy Joel Postpones Madison Square Garden Show Due to Viral Infection and Vocal Rest“I’m so sorry to let you know so close to show day, but I was hoping to be closer to a full recovery by now. Sadly, that hasn’t happened,” Piano Man says of final gig of 2022
Read more »
Billy Joel Postpones Madison Square Garden Show, Cites Lingering Viral InfectionBilly Joel has postponed his last Madison Square Garden concert of this year, citing a “viral infection.” The postponement was announced on Saturday evening for the planned Monday show.…
Read more »
Billy Joel cancels tonight’s show at MSG due to viral infectionJUST IN: BillyJoel has canceled tonight's show at MSG after contracting a viral infection -
Read more »
Billy Joel postpones final residency show of year due to 'viral infection''I’m disappointed to share that I’m under doctor’s orders for vocal rest due to a viral infection so unfortunately, I must postpone my Monday, December 19th concert at Madison Square Garden to June.'
Read more »
Billy Joel postpones Madison Square Garden concert due to 'viral infection''I was hoping to be closer to a full recovery by now,' Billy Joel said in a message to fans. 'Sadly, that hasn't happened.'
Read more »