FDA ruling: What is mifepristone?

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FDA ruling: What is mifepristone?
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Mifepristone blocks a hormone called progesterone, which helps the body maintain the inside of the uterus so a pregnancy can continue. A healthy uterine lining is what supports a fertilized egg, em…

Mifepristone usually doesn’t have many side effects, doctors say, but as with any drug, there can be short-lived ones.

Side effects of mifepristone may include dizziness, weakness, vomiting, headache, diarrhea, nausea, and fever or chills,Major adverse events like blood loss, hospitalization or a significant infection are “exceedingly rare,” happening in less than 0.3% of patients, according to the medical associations’ amicus brief.The mifepristone-misoprostol combination is the most common abortion method in the US.

This review said that across all studies of people who took only misoprostol, about 78% had complete abortions, and a viable pregnancy was terminated in more than 93% of the cases. At most, 0.2% of cases had serious complications that required a transfusion or hospitalization. People who take misoprostol on its own for an abortion typically need to take more for it to work, and the side effects can be more intense, said Dr. Melissa L. Wong, an obstetrician/gynecologist in Massachusetts and a fellow with Physicians for Reproductive Health.

“Misoprostol still works very well and is very safe,” Wong said. “Mifeprestone typically does not cause any side effects as it stops the pregnancy hormone. With misoprostol, some people may tolerate it a bit less because of some side effects like nausea, vomiting, sometimes things like diarrhea or a transient fever. Those are still safe and expected side effects, but they are still uncomfortable for anyone.

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