Frontiers | Mitigating co-circulation of seasonal influenza and COVID-19 pandemic in the presence of vaccination: A mathematical modeling approach

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Frontiers | Mitigating co-circulation of seasonal influenza and COVID-19 pandemic in the presence of vaccination: A mathematical modeling approach
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Similarities between COVID-19, cold and flu symptoms could lead to higher infections frontiersin

In our model, we took into account the multi-factorial interactions between influenza and COVID-19 in terms of additional epidemiological, clinical, and organizational burdens due to their comparable early symptoms, which can present a clinical challenge in determining the patient's disease type and overwhelm testing capacity, lowering the diagnosis rate. In this scenario, we observe that if testing capacity is increased per day, it will delay the peak of COVID-19 in addition to reducing it.

However, there are some limitations in the present study. To keep this model parsimonious, we did not include latent or asymptomatic stages of infection. We believe including these stages would not overly affect our predictions due to the majority of COVID-19 and flu cases being symptomatic, and therefore requiring diagnosis . Future studies may be extended to add these states if needed.

Our study has important practical implications for public health policy: It shows that effectively managing and controlling both influenza and COVID-19 outbreaks during the same season depend on ensuring optimal strategies in terms of vaccine coverage.The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author.BM, WW, and JW originated the research idea.

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