Genome sequence of COVID in a cat nearly identical to viral sequences found in people Penn
In a new report, researchers from the University of Pennsylvania's School of Veterinary Medicine and Perelman School of Medicine find that, for at least one example of apparent interspecies transmission, this crossing the species boundary did not cause the virus to gain a significant number of mutations., the scientists identified a domestic house cat, treated at Penn Vet's Ryan Hospital, that was infected with the delta variant of SARS-CoV-2 subsequent to an exposure from its owner.
"This did highlight the importance of sampling at multiple body sites," says Lennon."We wouldn't have detected this if we had just done a nasal swab." Working through the Penn Center for Research on Coronaviruses and Other Emerging Pathogens and Perelman School of Medicine microbiologist Frederic Bushman's laboratory, the team obtained a whole genome sequence of the cat's virus.
Not all variants of SARS-CoV-2 have been equally able to infect a wide range of hosts. For example, the original Wuhan strain could not naturally infect mice; later variants gained that ability. Scientists began seeing infections in cats and dogs from the early days of the pandemic, presumably infected through close contact with their owners.
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