New study builds the foundation for future success against brain decline, reversing decades of disappointment.
After decades of failure in Alzheimer’s disease research, scientists are buoyed by new findings that could mark a turning point in the field, offering hope that treatment may someday slow the grim deterioration of the brain.and presented to applause at a sold-out conference in San Francisco last week, showed a substantial reduction in damaging brain plaques and some modest slowing of cognitive decline in patients with early disease.
“This is really just a foothold,” he said. “It’s our first successful attempt to intervene in this complicated biology, and meaningfully intervene in a cascade of events.” Progress against the disease has been slow because, until recently, it was diagnosed too late, long after brain cells had already died. Now new blood tests can reveal the early onset of plaques and tangles in the brain before symptoms appear — giving intervention a chance.
“What does that mean in real life? It may mean that you can drive your car. It may mean that you can communicate for longer,” said Elizabeth Edgerly, executive director of the Alzheimer’s Association of Northern California and Northern Nevada. While there is wide variability in cognitive function, even in healthy people, “we’ve never seen anything like that.”
Pam Montana, from Danville, was diagnosed with Alzheimer’s disease in 2016. “Honestly, this is what this is keeping me going – these trials,- she said. “And hope. It’s all about hope.”
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