How a strategy based on testing helped eradicate smallpox

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How a strategy based on testing helped eradicate smallpox
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'Testing, testing, testing' has become the mantra of the fight against the coronavirus. Scientific experts all seem to agree the virus cannot be controlled without adequate testing. Via InsideScience.

confirmed cases are a small fraction of the true number. Without more testing we don't know what percentage of cases have been detected so far.now and smallpox in the 1970s is the availability of an almost perfect smallpox vaccine, developed in 1796, by the English physician Edward Jenner.

Two other factors helped: The vaccine could be freeze-dried so it was stable and transportable, and scientists at the drug company Wyeth developed the perfect delivery system, a bifurcated needle that administered an exact amount of vaccine into the dermis, the layer of skin below the epidermis, when the needle was jabbed twice -- essentially painless, no injections needed.Some people with COVID-19 can walk around without exhibiting symptoms.

For most of the world, it was possible to stop transmission by simply vaccinating everyone in sight. An elaborate intelligence network was set up to find where the virus was: Rewards were offered to people who reported a case, and teams of investigators and vaccinators would swarm into the area showing pictures of smallpox victims and asking if people had seen someone like that.

Medical laboratory scientist, Alicia Bui, runs a clinical test in the Immunology lab at UW Medicine looking for antibodies against SARS-CoV-2, a virus strain that causes coronavirus disease on April 17, 2020, in Seattle. Without a vaccine or reliable visible signs like the smallpox pustules, it probably won't be possible to completely eradicate COVID-19 anytime soon. But with more widespread testing, we may have a chance of keeping it under control.

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