The world's first CRISPR tool is about to be approved for a rare blood condition, but in the not too distant future, millions of people will be editing their genes to treat everything from cancer to high cholesterol.
THE bouts of terrible pain began further back than Victoria Gray can remember. Her grandmother would try to ease the discomfort with hot towels and medication, but it was fruitless. “I was born having to endure pain,” she says. “It was a life that I felt wasn’t worth living.”
Gray has an inherited condition known as sickle cell disease, which causes red blood cells to form an abnormal “sickle” shape that can block capillaries, causing pain and sometimes organ damage. As Gray aged, her pain got worse. On one occasion, she temporarily lost the use of her arms and legs. By her 30s, Gray required in-home care.
The treatment involved will probably be given the green light by regulators in the US, UK and Europe soon, which will make it the firstThere is now no doubt that this technology – used to edit genes – can treat and potentially even cure a huge range of conditions.
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