Increased incidence of hypertensive disorders of pregnancy in young Americans Pregnancy Cardiovascular Disease Eclampsia Heart HeartFailure Mortality Obesity JAMANetworkOpen
By Dr. Priyom Bose, Ph.D.Aug 28 2022Reviewed by Benedette Cuffari, M.Sc. Hypertensive disorders of pregnancy , which include preeclampsia, eclampsia, and hypertension, are leading causes of mortality and morbidity in pregnant individuals. As a result, HDP has become a significant health crisis among pregnant individuals in the United States.
Background In the past decade, the rate of HDP has almost doubled to 8% of pregnant women. The highest incidence of HDP has been reported among non-Hispanic American Indians, non-Hispanic Black individuals, and Alaska Native individuals. About the study A total of 38,771,194 nulliparous individuals between the ages of 15 and 44 were identified between 1995 and 2019. Individuals without enough relevant data on HDP and pre-pregnancy hypertension were excluded from the cohort.
A persistent occurrence of HDP, irrespective of age, birth cohort, and delivery period, was observed among self-identified non-Hispanic American Indian or Alaska Native and non-Hispanic Black individuals. In addition, a significant increase in HDP incidence in these groups was reported from 2010 to 2019.
For example, pregnant women with a history of cardiovascular disease were at an increased risk of developing HDP. This factor also increased mortality and morbidity rates, as well as the risk of cardiovascular health issues for the offspring. The cohort analysis also revealed a tendency for greater onset of new HDP among older and non-Caucasian pregnant individuals at delivery.
More research using pregnancy-specific cohorts with long-term follow-up is needed to understand the association between obesity and HDP better.
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