International trade of colistin in animal feed continues unabated Antibiotic AntibioticResistance Ecoli Food Meat Medicine Plasmid Prophylaxisa LancetMicrobe cardiffuni UniofOxford
By Pooja Toshniwal PahariaMar 22 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in the journal The Lancet’s Microbe, researchers investigate Enterobacterales species resistance to colistin in Pakistan. Moreover, the researchers report on colistin import and export, use, and socioeconomic variables associated with colistin resistance.
The spread of plasmid-mediated colistin resistance in Enterobacterales in the environment, among humans and food-producing animals has raised population health concerns. Even though colistin resistance decreased in China following its ban, colistin manufacture and export as pharmaceutical raw materials or feed additives continues.
Swab specimens from backyard poultry cloaca, commercial broiler cloaca, buffalo and cattle rectums, and human rectums were obtained. In addition, samples of wild birds’ droppings, wastewater and fresh water, chicken, buffalo, and cattle meat, and poultry flies were obtained from 131 locations across Faisalabad for mobile colistin resistance -1,3-positive E. coli testing.
Omics eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy Further, individuals were enrolled from veterinary medicine stores and poultry farms in Nigeria and Pakistan for structured-type questionnaire-based interviews. Data on global manufacturing and trade, value analysis, and import-export routes for colistin PRM, finished pharmaceutical products , and feed additives were obtained from 2017 to 2021 export datasets.
200 inpatients were enrolled at the Allied Hospital of Pakistan between November 15, 2018, and December 14, 2018, to obtain rectal swab specimens. In addition, 21 individuals were enrolled between January 1, 2020, and December 31, 2020, from drug stores and poultry farms in Nigeria and Pakistan for interviews.
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