Is COVID-19 severity of infection a new risk factor for chronic pain? PLOSONE UpstateNews StonyBrookMed chronicpain COVID19 coronavirus covid infection pain
By Pooja Toshniwal PahariaJun 27 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in PLOS ONE, researchers investigated whether severe acute respiratory syndrome coronavirus 2 infection severity could increase the risk of chronic pain.
Moreover, chronic pain is complicated to manage. However, population-level data on the association between the severity of SARS-CoV-2 infections and pain development are limited, warranting further research. The NHIS survey was conducted by the National Center for Health Statistics for the Centers for Disease Control and Prevention . The participants were interviewed in person and propensity score-matched in a 1.0:1.0:1.0 ratio to assess the prime study outcome of pain frequency among matched individuals.
Results Among the study participants, 12,131 never tested SARS-CoV-2-positive , 1,440 experienced none or mild COVID-19 symptoms , whereas 1,764 experienced moderate-to-severe COVID-19 symptoms . While 11,965 participants reported no or infrequent pain , 3370 experienced chronic pain. The covariates were independently associated with SARS-CoV-2 infection status and chronic pain. Before matching, compared to participants testing SARS-CoV-2-negative, those with positive COVID-19 results showed an increased likelihood of being of working age, non-white, with a lower level of education, a lower household income, and an increased prevalence of comorbidities.
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