In 1997, Dr Yuk Ming Dennis Lo, a 2022 Lasker Awardee, published a seminal article showing that cell-free fetal DNA could be detected in maternal blood. That was the beginning of prenatal testing eventually leading to present day NIPT.
With the commercial launch of noninvasive prenatal testing in 2011, healthcare centers around the world quickly embraced the technology as a safe alternative to more invasive methods, such as, for identifying fetal abnormalities. NIPT is now available in over 60 countries and is widely used by clinicians, according to the Lasker Foundation, which granted him the 2022 Lasker DeBakey Clinical Medical Research Award, along with a $250,000 prize.
Iris Krishna, MD, MPH, director of Perinatal Quality in the Emory Perinatal Center at Emory University School of Medicine, Atlanta, said Lo's work has also provided opportunities to screen for other genetic disorders, such as microdeletion syndromes and single gene disorders At the time, according to Lasker, no other institution was providing this information. The World Health Organization created summaries of daily COVID-19 counts, but the data were not as accessible. Gardner said timely and obtainable information was crucial to craft nimble and rational strategies for combating the pandemic.
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