Jimmy Garoppolo’s first start of the 49ers’ 2022 season comes against Russell Wilson and the Broncos.
The 49ers are back in the national spotlight Sunday night as they head to Denver to face the Broncos and new quarterback Russell Wilson, acquired this offseason in a deal from Seattle.
Of course, the Niners are quite familiar with Wilson’s work with the Seahawks. He’s been a constant thorn in the side of the 49ers, going 17-4 in his 21 career games. His counterpart is also a familiar face, taking over again after being supplanted. Jimmy Garoppolo will be back under center for the 49ers after Trey Lance, who started the first two games of the season, suffered a broken ankle in the Week 2 win over the Seahawks.
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