New antibiotic that slays superbugs discovered in 'dark matter' microbes from North Carolina soil

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New antibiotic that slays superbugs discovered in 'dark matter' microbes from North Carolina soil
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Deadly superbugs are unlikely to develop resistance to a new antibiotic produced by bacteria, scientists say.

A new antibiotic made by lab-grown bacteria can kill"superbugs" without driving the germs to become more resistant to treatment, an early study suggests.

"Clovibactin is a chemically novel antibiotic that comes from what we call the 'dark matter' of bacteria — bacteria that have not been grown in the lab before," Weingarth said."It's nontoxic in animal models and works better than the gold-standard antibiotic vancomycin," which is used to treat bacterial infections that show resistance to other drugs, yet has started to become ineffective against some strains of bacteria.

The team found that clovibactin can kill two dangerous superbugs: methicillin-resistant Staphylococcus aureus, or MRSA, and Enterococcus faecalis bacteria that are resistant to vancomycin. MRSA can cause life-threatening infections when it enters the body through wounds or during surgery, and E. faecalis causes a variety of infections, including urinary tract infections.

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