Eluned Morgan said health boards will find it 'difficult' to find savings in budgets.
Asked whether there would be staff cuts, Ms Morgan said: "There is a turnover of staff and the question perhaps will be whether we can replace those who leave the service.
"So, those are some of the questions I expect health boards to come up with answers for in the next few weeks. "Once we know where we can make those savings then of course we will be straight with the public in terms of what that will mean."Betsi Cadwaladr health board, which was put into into special measures in February, has a £140m overspend.
Chairman Dyfed Edwards said: "The government ask is to respond to a reducing budget within the health board at the moment but also to look wider, to see if we can produce more savings. "That's part of the discussion with government - for them to have a clear picture of what that reducing budget will look at, and what does it mean in terms of the provision of services."
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