Now that researchers understand the cause of the ailment, some are working to eradicate it.
found that “morning sickness” during pregnancy is the result of a spike in the levels of a stress response hormone called growth and differentiation factor 15 .in 2023, she found that women who are genetically predisposed to low levels of GDF15 before pregnancy can become hypersensitive to its rapid rise during pregnancy, leading them to experience severe morning sickness, otherwise known as hyperemesis gravidarum .
Given animals that lay eggs such as snakes and octopuses experience symptoms of nausea and appetite loss as well, it may have also evolved to prevent mothers-to-be venturing out into a hostile environment of predators, pathogens and extreme weather. These include a nearly three-fold risk of the baby being born before 34 weeks and, later in life, a 25 per cent higher risk of depression and social problems as well as a greater likelihood of being diagnosed with autism spectrum disorder, ADHD, childhood cancer and respiratory and cardiovascular disease.
“The psychosocial part of it is horrible. It’s really debilitating,” says Livingstone. “They can’t work, they can’t socialise with their friends, they can’t look after their own kids because they feel so sick.” COPE recently conducted a survey of women who have HG and found 60 per cent didn’t feel they had support or understanding from those around them. Not only does this affect their relationships, says Highet: “They give up going to others about it.”The current approach in many hospitals involves “really old-school treatment”, says Livingstone.
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