'Off-Label' Drugs for Kids Raises Concerns

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'Off-Label' Drugs for Kids Raises Concerns
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When a child gets sick, doctors are increasingly relying on what's known as 'off-label' use of medications, a new study says.

"Off-label doesn't mean a drug is harmful. There's often good evidence behind the use of off-label drugs," said study senior author Dr. Daniel Horton. He's an assistant professor of pediatrics and epidemiology at the Rutgers Robert Wood Johnson Medical School in New Brunswick, N.J.

of medications. This left a large gap in knowledge. Over time, legislation and policies to require more research have been developed," Horton said., available online Sept. 16. He said sometimes parents don't want their children involved in drug research trials. Another issue, he noted, is that"some diseases are just less common in children," such asHorton and his colleagues used nationally representative surveys from doctors' offices, including about 1.74 billion visits for children under 18. During these visits, 18.5% of children were given a prescription for one or more off-label drugs.

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