One in three men over 15 globally have at least one incidence of genital HPV, underscoring the need to include males in HPV prevention strategies. The prevalence remains high from young adulthood through later life, particularly for high-risk HPV types linked to cancers.
By Dr. Chinta SidharthanSep 6 2023 In a recent study published in The Lancet Global Health, researchers conducted a systematic review and meta-analysis to understand the regional and global pooled, overall, and type and age-specific prevalence estimates of genital human papillomavirus infection in males.
In men, HPV infections often manifest as anogenital warts and contribute to increased infection transmission rates. The type 16 strain of HPV is also linked to anal, penile, and oropharyngeal cancers. However, while many epidemiological studies have examined the prevalence and consequences of HPV infections in women, the data on prevalence rates among men have been lacking.
For the meta-analysis, only data on the mucosal α genus of HPV was extracted since the viral strains that cause anogenital warts in men and the major oncogenic types of HPV are present in this genus. The random-effects model was used during the meta-analysis to estimate the regional and global prevalence for any type of HPV, high-risk HPV, and individual types of HPV in an age-specific manner.
Related StoriesThe study also showed that irrespective of age, sexually active men were a genital HPV infection reservoir, and it is imperative to include men in the worldwide strategies for HPV prevention to reduce HPV-associated morbidity in men and eventually eliminate HPV-related diseases such as cervical cancer.
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