Scientists hope that a new class of treatments for alcohol use disorder, smoking and other addictive behaviors is on the horizon.
Few studies have been done on humans, but six clinical trials are now underway investigating how semaglutide may alter people's drinking and smoking habits.
GLP-1s specifically decrease the amount of dopamine the brain releases after people indulge in behaviors like drinking, smoking or even eating a sweet dessert, according to Dr. Steven Batash, a gastroenterologist who provides nonsurgical weight loss procedures in Queens, New York. But even if those trials confirm that GLP-1s can reduce addictive behaviors in humans,"it will most likely work for some patients and not others," according to Leggio.
The reason may be that"leaner patients" treated with exenatide experienced a larger decrease in blood sugar, which might be associated with increased cravings for alcohol, the researchers wrote in the study.It's also unclear how long the anti-addiction effect of GLP-1s will last.
It may take years, but scientists and other health experts hope that a new class of treatments for alcohol use disorder, smoking and other addictive behaviors is on the horizon.
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