Some smokers lose their cravings after experiencing damage to specific areas of the brain, suggesting these areas form a network that somehow fuels the habit
A brain circuit involved in addiction has been identified after researchers analysed smokers who immediately lost their nicotine cravings following brain damage.
, is approved to help people quit smoking in the US. It involves going to a clinic where doctors hold a small device over the head that temporarily boosts activity in part of the brain. But it is unclear how it works and it is not used widely.
But the quitters did not have damage in a fourth key region of this circuit, called the medial prefrontal cortex. Located in the centre of the forehead, this region seems to act as an inhibitor, suppressing activity elsewhere in the network. Targeting the medial prefrontal cortex via TMS could help people overcome addiction, says Joutsa.
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