The report showed an approximately 25 percent reduction in 10 of the 12 symptoms studied, including the common complaints of lingering fatigue and brain fog.
the findings in an online post that emphasizes the urgency of developing treatments for what is now widely recognized as a mass-disabling condition.“We have no treatment that has been validated to treat Long Covid,” Topol wrote. “Rigorous, randomized, definitive clinical trials are long overdue.”
“We could do a long-term follow up to determine if both groups have the same or different rates of persistent symptoms,” said David Putrino, director of rehabilitation innovation at Mount Sinai Health System in New York.Pfizer said the company is “working with multiple institutions toward the start of studies to evaluate Paxlovid for potential use in addressing long covid.” In its 2022 financial guidance, the company reported Paxlovid revenue of $22 billion.
There is no data to show whether those previously healthy young people would reap the same benefits as people at risk of severe disease. Putrino cautioned that the study’s promising results may be related to the antiviral’s ability to reduce the severity of acute illness that can lead to lingering complications such as lung fibrosis from pneumonia, pericarditis from inflammation and what’s known as post-ICU syndrome, rather than the other symptoms he commonly sees.
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