The WHO estimates 290,000 to 650,000 people worldwide die of flu-related causes every year. About 1.1 million people in the U.S. have died from COVID-19.
"Even with existing seasonal influenza vaccines, the burden of this virus is severe across the world," Anderson said.
The Phase 1 study will take place in the U.S. and enroll 180 volunteers from 18-64 years old with a six-month follow-up period, the companies said.Felipe Sanchez gets a COVID-19 booster shot from pharmacist Patricia Pernal during an event hosted by the Chicago Department of Public Health at the Southwest Senior Center on September 09, 2022 in Chicago.
Vaccines utilizing messenger RNA, or mRNA, teach cells how to make a protein that will trigger an immune response that protects a person from becoming seriously ill from a disease, according to the CDC. Pfizer-BioNTech’s mRNA COVID-19 vaccine was the first time mRNA vaccine technology was approved for use, closely followed by Moderna’s mRNA COVID-19 vaccine.The molecule was first discovered in the early 1960s and research into its uses in medical treatment progressed into the 1970s and 1980s, according to Johns Hopkins University’s School of Public Health.
A flu vaccine based on mRNA was tested on mice in the 1990s, but the first vaccines for rabies and influenza weren’t tested on humans until recently. Kuritzkes said no deaths from those vaccines were reported in those trials.Scientists say mRNA only lasts in the body for a short period of time before rapidly degrading, making it unlikely that it would cause long term effects.Wendy Gonzalez, RN, prepares a flu shot at Huntington Village Pediatrics, in Huntington, New York on December 8, 2021.
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