Pfizer booster spurs immune response to new omicron subtypes

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Pfizer booster spurs immune response to new omicron subtypes
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Preliminary data shows that the updated booster generated antibodies good against four additional omicron subtypes, including the particularly worrisome BQ.1.1, the companies said.

Pfizer and its partner BioNTech said their updated booster generated virus-fighting antibodies that can target four additional omicron subtypes, including the particularly worrisome BQ.1.1.

It’s not the only hint that the updated boosters may broaden protection against the still mutating virus. Moderna recently announced early evidence that its updated booster induced BQ.1.1-neutralizing antibodies. The BA.5 variant was responsible for about 30% of new cases in the U.S. as of Nov. 12, according to the Centers for Disease Control and Prevention, but two new variants have been crowding out the once-dominant strain in recent weeks. The BQ.1.1. variant now accounts for 24% of cases, up from 2% in early October, and the close cousin BQ.1 accounts for 20% of cases.

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