Pig kidney works in brain-dead man for a record two months, raising hope for animal-human transplants

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Pig kidney works in brain-dead man for a record two months, raising hope for animal-human transplants
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Dr Robert Montgomery, the transplant surgeon who led the experiment, sees animal-to-human transplants as crucial to ease the organ shortage.

Dozens of doctors and nurses silently lined the hospital hallway in tribute: For a history-making two months, a pig’s kidney worked normally inside a brain-dead man on the gurney rolling past them.

“It’s a combination of excitement and relief,” Dr Robert Montgomery, the transplant surgeon who led the experiment, told“Two months is a lot to have a pig kidney in this good a condition. That gives you a lot of confidence” for next attempts.”Montgomery, himself a recipient of a heart transplant, sees animal-to-human transplants as crucial to ease the nation’s organ shortage. More than 100,000 people are on the national waiting list, most who need a kidney, and thousands will die waiting.

Miller had collapsed and was declared brain-dead, unable to donate his organs because of cancer. After wrestling with the choice, Miller-Duffy donated the Newburgh, New York, man’s body for the pig experiment. She recently got a card from a stranger in California who’s awaiting a kidney transplant, thanking her for helping to move forward desperately needed research.

But soon after, doctors measured a slight decrease in the amount of urine produced. A biopsy confirmed a subtle sign that rejection was beginning – giving doctors an opportunity to tell if it was treatable. Sure enough, the kidney’s performance bounced back with a change in standard immune-suppressing medicines that patients use today.

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