Pregnancy's profound impact: How motherhood reshapes the female brain

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Pregnancy's profound impact: How motherhood reshapes the female brain
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Pregnancy's profound impact: How motherhood reshapes the female brain Pregnancy BrainFunction FemaleHealth Neuroplasticity Neuroinflammation Cognition BrainAging MaternalAge TrendsNeuro UBC goteborgsuni UofT

By Dr. Priyom Bose, Ph.D.Apr 30 2023 Scientists have pointed out the importance of studying sex as a biological variable. However, it is not well understood how female-specific factors, such as pregnancy and menopause, affect the brain. Recently, scientists reviewed the short-term and long-term impact of pregnancy on neuroinflammation, cognition, and neuroplasticity. This review is available in the journal Trends in Neurosciences.

During pregnancy, the production of estrogens rises by 300 times and then suddenly declines after the expulsion of the placenta. Hormones specific to the placenta, such as estriol, placental lactogen, and relaxin, are absent outside of pregnancy. Research on the effects of these hormones is essential because pregnancy could change the course of many neurological disorders, e.g.

The Long-term Effects of Pregnancy on Physiology Prior pregnancy has been associated with lower estradiol levels and shorter menstrual cycles in middle age. Also, increased parity appears to be correlated with increased obesity in middle-aged postmenopausal women.

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