Singapore and India both fought off the most highly evolved COVID variants yet, but the U.S. can’t match the way they did it.
in Europe and the U.S. are both more contagious than previous forms of the SARS-CoV-2 virus and more immune-evasive. That is, they reduce the effectiveness of many of the leading vaccines—and totally thwart monoclonal antibody therapies, according to some studies.. Neither country has logged a sustained increase in COVID deaths.
BQ.1 has an advantage over other COVID subvariants thanks to three major mutations on its spike protein, the part of the SARS-CoV-2 virus that helps it grab onto and infect our cells. These mutations make BQ.1 more contagious than its cousins. XBB hasThese and other mutations also give BQ.1 and XBB their shared ability to evade antibody therapies. These therapies aren’t the only way to treat COVID, of course—there are antiviral drugs and treatments that don’t include doses of antibodies.
is fully vaccinated with one of four approved vaccines: the two messenger-RNA jabs from Pfizer and Moderna as well as separate protein-based and inactivated-virus vaccines from Novavax and Sinovac, respectively.are “fully” vaccinated, most with two doses of mRNA. Even more impressive, a whopping eight out of 10 Singaporeans have gotten a booster shot, as well—compared to around three out of 10 Americans. There might be more vaccine-induced antibodies in Singapore than anywhere else.
Decoupling is one of the most important trends as the COVID pandemic grinds toward its fourth year. Thanks to a wall of antibodies from vaccines and past infection, the global death rate has been slowly dropping even as new variants and subvariants drive back-to-back waves of infections. That one-day increase appears to be a result of uneven reporting from regional health officials, which has been a consistent problem in India. After all, no major increase in cases accompanied the recent increase in deaths. And there were similar isolated mortality spikes in January, March, and April.
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